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Genkyotex (Euronext Paris Brussels: FR0013399474 GKTX) (Paris:GKTX) (Brussels:GKTX), a biopharmaceutical aggregation and the baton in NOX therapies, today appear banknote and banknote equivalents of €1.2 actor as of December 31, 2020. The absolute banknote and banknote equivalents accommodate banknote aerodrome to the end of February 2021. After this date Genkyotex will be appropriate to armamentarium the advancing operations with new capital. Calliditas Therapeutics, the majority actor of Genkyotex, has bidding its absorbed to participate in such approaching financings on a pro rata basis. Until such costs has occurred, Calliditas will abutment Genkyotex by way of debt costs to accredit the Aggregation to accommodated its liabilities as they abatement due and to backpack on its accustomed business after any cogent abbreviation of operations.

Business update

On August 13, 2020, the Aggregation appear the acceding by Calliditas to access 7,236,515 accustomed shares of Genkyotex, apery 62.7% of the allotment basic and voting rights from the Company’s better shareholders and administering team.

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On December 17, 2020, the Aggregation appear the after-effects of the breakable offer, according to the after-effects appear on December 16, 2020 by the Autorité des marchés financiers (AMF), a absolute of 2,885,161 shares were tendered to the accessible offering. Afterward the abutting of the accessible offer, Calliditas captivated 10,121,676 shares of the Aggregation apery 86.24% of the allotment basic and voting rights of the Company.

Clinical highlights

Q4 2020 Banking highlights

On December 31, 2020, the Company’s banknote and banknote equivalents totaled €1.2 actor vs. €3.6 actor on September 30, 2020. The Company’s banknote bake over the FY 2020 was primarily apprenticed by R&D costs accompanying to the alertness of the End-Of-Phase 2 affair with the FDA and the Appearance 1 abstraction to investigate college dosage with setanaxib.

The Aggregation expects its accepted assets to abutment advancing operations until the end of February 2021, demography into annual the facts and assumptions abundant in agenda 2.1 “Going concern” of the December 31, 2019 circumscribed banking statements and the abridged circumscribed acting banking statements able in accordance with IFRS for the six-month aeon concluded June 30, 2020. Genkyotex will be appropriate to armamentarium the advancing operations with new capital. Calliditas Therapeutics, the majority actor of Genkyotex, has bidding its absorbed to participate in such approaching financings on a pro rata basis. Until such costs has occurred, Calliditas will abutment Genkyotex by way of debt financing.

Financial after-effects to September 30, 2020

As allotment of the accounting alliance action of Calliditas, the Aggregation able circumscribed banking statements for the nine-month aeon concluded September 30, 2020 beneath IFRS, as issued by the International Accounting Standards Board.

These banking statements are accessible in the Investors area of the Company’s website. The Aggregation does not plan going-forward to address on standalone nine-month banking advice or on annual banking advice (other than in affiliation to its annual banknote and banknote equivalents position).

In bags of euros

Nine-month periodended September 30,2020

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At December 31,2019

Other Income

35

142

Research Development expenses

(9,627)

(6,305)

Subsidies and Analysis Tax Credit

356

899

General Administrative expenses

(1,757)

(2,160)

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Operating loss

(10,993)

(7,425)

Net loss

(11,017)

(7,203)

Net accident per allotment (in euros)

(0.99)

(0.88)

Given its date of development, the Aggregation has not generated any sales to date, as all of its artefact candidates are in the Analysis Development (R&D) phase.

The circumscribed net accident as at September 30, 2020 is €11,017 thousand adjoin €7,203 thousand as at December 31, 2019. This access is mainly apprenticed by the crime of the SIIL arrangement as a aftereffect of the appulse of Covid-19 on the development timelines (negative appulse of €5.8 M), partially account by the abridgement of R&D costs due to the end of the Appearance 2 analytic balloon with setanaxib in primary biliary cholangitis (PBC) and bargain G&A costs.

Governance

Following the closing of the off-market block barter on November 3, 2020, the associates of the lath of admiral added than Elias Papatheodorou, Chief Executive Officer, resigned. Elmar Schnee, Chairman of the lath of Calliditas, Renée Aguiar-Lucander, Chief Executive Officer of Calliditas and Jonathan Schur, Group Accepted Counsel of Calliditas, accept been appointed as associates of the Lath of directors. Elmar Schnee has been adopted President of the Lath of directors. Dr. Philippe Wiesel, Executive Vice President and Chief Medical Officer of Genkyotex, has larboard the Aggregation to accompany new able projects. He will abide as a adviser to Calliditas.

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COVID-19 update

In the ambience of the COVID-19 pandemic, the Aggregation continues to carefully adviser the change of the official guidelines and recommendations in adjustment to assure its advisers and contractors. The Aggregation has additionally implemented strategies to abate the appulse of the all-around abeyance on its business and operations.

To date, except for the crime of the SIIL arrangement (see above), the COVID-19 communicable has had a bound appulse on the Company’s operations. Genkyotex will abide to adviser the appulse of the COVID-19 pandemics on the administering of analytic trials and discussions with bloom authorities and, depending on the change of the pandemics and of its potentially absolute appulse on such trials and discussions, will accumulate the bazaar informed.

About Genkyotex

Genkyotex is the arch biopharmaceutical aggregation in NOX therapies, listed on the Euronext Paris and Euronext Brussels markets. Its arch belvedere enables the identification of orally accessible small-molecules which selectively arrest specific NOX enzymes that amplify assorted ache processes such as fibrosis, inflammation, affliction processing, blight development, and neurodegeneration. Genkyotex is developing a action of first-in-class artefact candidates targeting one or assorted NOX enzymes. The advance artefact candidate, setanaxib (GKT831), a NOX1 and NOX4 inhibitor has apparent affirmation of anti-fibrotic action in a Appearance II analytic balloon in primary biliary cholangitis (PBC). Analytic trials in PBC and arch and close blight with setanaxib are actuality planned in 2021 and investigator led studies in Type 1 Diabetes and Branch Ache (DKD) and in idiopathic pulmonary fibrosis (IPF), a abiding lung ache that after-effects in fibrosis of the lungs, are ongoing.

For added information, amuse go to www.genkyotex.com

Disclaimer This columnist absolution may accommodate advanced statements by the aggregation with account to its objectives. Such statements are based aloft the accepted beliefs, estimates and expectations of Genkyotex’s administering and are accountable to risks and uncertainties such as the company’s adeptness to apparatus its called strategy, chump bazaar trends, changes in technologies and in the company’s aggressive environment, changes in regulations, analytic or automated risks and all risks affiliated to the company’s growth. These factors as able-bodied as added risks and uncertainties may anticipate the aggregation from accomplishing the objectives categorical in the columnist absolution and absolute after-effects may alter from those set alternating in the advanced statements, due to assorted factors. After actuality exhaustive, such factors accommodate uncertainties complex in the development of Genkyotex’s products, which may not succeed, or in the commitment of Genkyotex’s articles business authorizations by the accordant authoritative authorities and, in general, any agency that could affects Genkyotex’s accommodation to commercialize the articles it develops. No agreement is accustomed on advanced statements which are accountable to a cardinal of risks, conspicuously those declared in the accepted allotment certificate filed with the AMF on April 30, 2020 beneath cardinal D.20-0434, and those affiliated to changes in bread-and-butter conditions, the banking markets, or the markets on which Genkyotex is present. Genkyotex articles are currently acclimated for analytic trials alone and are not contrarily accessible for administration or sale

Contacts:

GENKYOTEXAlexandre GrassinCFOTel.: 33 (0)5 61 28 70 [email protected]

NewCapDušan OrešanskýTel.: 33 1 44 71 94 [email protected]

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